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Using two separate drugs to lose weight can be very effective you will find combinations before the FDA now awaiting approval. When dealing with weight reduction and the those who go through it you need to err along the side of caution and permit the FDA do its job and demand some investigation be done so the public is aware of the side effects and dangers of the medications before we drive them. Keep in mind that drug companies are in business to generate money and that they would say anything to keep people on his or her medications. Researchers found that participants taking this drug to get a year, lost excess weight within a month and have kept the weight off throughout the 56 weeks of the study. Contrave is a combination from the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs which are made up of several active ingredient, that might make them more efficient and safer. Combo-pilling is the newest fad or even better the newest in the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for weight loss has been around since the eighties. The biggest reason that using a combination of pills is now popular will be the fact that since right now there aren't any long term prescription diet pills that have been authorized by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be licensed by the FDA. Seizures can be a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug could also raise blood pressure levels and heartbeat, and mustn't be used in people with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure and pulse rate and must not be used in patients with uncontrolled high blood pressure levels, in addition to by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients using a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients towards the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking. Acamprosate also actively works to eliminate the desire to drink through the elimination of the the cravings for drinking alcohol. The major difference between Naltrexone and Acamprosate is Acamprosate just isn't yet obtainable in the United States. While it may be widely studied in Europe the precise chemical reason that it works is still unknown. It is believed that it disrupts receptors within the brain which process glutamate, which in essence alters just how ones body reacts to alcohol intake. Several of the European research shows a lot of promise with Acamprosate because some of the patients had an almost double effectiveness for staying sober.